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Upregulation of miR-181s reverses mesenchymal transition by targeting KPNA4 in glioblastoma

The goal of this work was to explore the most effective miRNAs affecting glioblastoma multiforme (GBM) phenotype transition and malignant progression. We annotated 491 TCGA samples’ miRNA expression profiles according to their mRNA-based subtypes and found that the mesenchymal tumors had significant...

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Detalles Bibliográficos
Autores principales: Wang, Hongjun, Tao, Tao, Yan, Wei, Feng, Yan, Wang, Yongzhi, Cai, Jinquan, You, Yongping, Jiang, Tao, Jiang, Chuanlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539550/
https://www.ncbi.nlm.nih.gov/pubmed/26283154
http://dx.doi.org/10.1038/srep13072