Three-dimensional electron microscopy reconstruction and cysteine-mediated crosslinking provide a model of the type III secretion system needle tip complex

Type III secretion systems are found in many Gram-negative bacteria. They are activated by contact with eukaryotic cells and inject virulence proteins inside them. Host cell detection requires a protein complex located at the tip of the device's external injection needle. The Shigella tip compl...

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Detalles Bibliográficos
Autores principales: Cheung, Martin, Shen, Da-Kang, Makino, Fumiaki, Kato, Takayuki, Roehrich, A Dorothea, Martinez-Argudo, Isabel, Walker, Matthew L, Murillo, Isabel, Liu, Xia, Pain, Maria, Brown, James, Frazer, Gordon, Mantell, Judith, Mina, Petros, Todd, Thomas, Sessions, Richard B, Namba, Keiichi, Blocker, Ariel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539596/
https://www.ncbi.nlm.nih.gov/pubmed/25353930
http://dx.doi.org/10.1111/mmi.12843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539596/
https://www.ncbi.nlm.nih.gov/pubmed/25353930
http://dx.doi.org/10.1111/mmi.12843

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