Identification of in vitro and in vivo disconnects using transcriptomic data

BACKGROUND: Integrating transcriptomic experiments within drug development is increasingly advocated for the early detection of toxicity. This is partly to reduce costs related to drug failures in the late, and expensive phases of clinical trials. Such an approach has proven useful both in the study...

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Detalles Bibliográficos
Autores principales: Otava, Martin, Shkedy, Ziv, Talloen, Willem, Verheyen, Geert R, Kasim, Adetayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539666/
https://www.ncbi.nlm.nih.gov/pubmed/26282683
http://dx.doi.org/10.1186/s12864-015-1726-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539666/
https://www.ncbi.nlm.nih.gov/pubmed/26282683
http://dx.doi.org/10.1186/s12864-015-1726-7

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