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Harmful somatic amino acid substitutions affect key pathways in cancers

BACKGROUND: Cancer is characterized by the accumulation of large numbers of genetic variations and alterations of multiple biological phenomena. Cancer genomics has largely focused on the identification of such genetic alterations and the genes containing them, known as ‘cancer genes’. However, the...

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Detalles Bibliográficos
Autores principales: Niroula, Abhishek, Vihinen, Mauno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539680/
https://www.ncbi.nlm.nih.gov/pubmed/26282678
http://dx.doi.org/10.1186/s12920-015-0125-x