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MicroRNA-132 promotes estradiol synthesis in ovarian granulosa cells via translational repression of Nurr1

BACKGROUND: Estrogen synthesis is an important function of the mammalian ovary. Estrogen plays important roles in many biological processes, including follicular development, oocyte maturation and endometrial proliferation, and dysfunctions in estrogen synthesis contribute to the development of poly...

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Detalles Bibliográficos
Autores principales: Wu, Shaogen, Sun, Haixiang, Zhang, Qun, Jiang, Yue, Fang, Ting, Cui, Isabelle, Yan, Guijun, Hu, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539686/
https://www.ncbi.nlm.nih.gov/pubmed/26282993
http://dx.doi.org/10.1186/s12958-015-0095-z