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Insulin and IGF-1, but not 17β-estradiol, alter the subcellular localization of MIER1α in MCF7 breast carcinoma cells

BACKGROUND: MIER1α is a transcriptional regulator that interacts with estrogen receptor α and inhibits estrogen-stimulated growth of breast carcinoma cells. Interestingly, analysis of MIER1α subcellular localization in breast samples revealed a stepwise shift from the nucleus to the cytoplasm during...

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Detalles Bibliográficos
Autores principales: Li, Shengnan, Paterno, Gary D., Gillespie, Laura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539687/
https://www.ncbi.nlm.nih.gov/pubmed/26281834
http://dx.doi.org/10.1186/s13104-015-1336-0