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diffHic: a Bioconductor package to detect differential genomic interactions in Hi-C data

BACKGROUND: Chromatin conformation capture with high-throughput sequencing (Hi-C) is a technique that measures the in vivo intensity of interactions between all pairs of loci in the genome. Most conventional analyses of Hi-C data focus on the detection of statistically significant interactions. Howe...

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Detalles Bibliográficos
Autores principales: Lun, Aaron T.L., Smyth, Gordon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539688/
https://www.ncbi.nlm.nih.gov/pubmed/26283514
http://dx.doi.org/10.1186/s12859-015-0683-0