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Xist localization and function: new insights from multiple levels

In female m ammals, one of the two X chromosomes in each cell is transcriptionally silenced in order to achieve dosage compensation between the genders in a process called X chromosome inactivation. The master regulator of this process is the long non-coding RNA Xist. During X-inactivation, Xist acc...

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Detalles Bibliográficos
Autores principales: Cerase, Andrea, Pintacuda, Greta, Tattermusch, Anna, Avner, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539689/
https://www.ncbi.nlm.nih.gov/pubmed/26282267
http://dx.doi.org/10.1186/s13059-015-0733-y