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Transcriptional analysis of immune-related gene expression in p53-deficient mice with increased susceptibility to influenza A virus infection

BACKGROUND: p53 is a tumor suppressor that contributes to the host immune response against viral infections in addition to its well-established protective role against cancer development. In response to influenza A virus (IAV) infection, p53 is activated and plays an essential role in inhibiting IAV...

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Detalles Bibliográficos
Autores principales: Yan, Wenjun, Wei, Jianchao, Deng, Xufang, Shi, Zixue, Zhu, Zixiang, Shao, Donghua, Li, Beibei, Wang, Shaohui, Tong, Guangzhi, Ma, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539693/
https://www.ncbi.nlm.nih.gov/pubmed/26282854
http://dx.doi.org/10.1186/s12920-015-0127-8