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Increased CTLA-4(+) T cells and an increased ratio of monocytes with loss of class II (CD14(+) HLA-DR(lo/neg)) found in aggressive pediatric sarcoma patients

BACKGROUND: There is little information regarding the composition of peripheral blood immunity in sarcoma patients and even less in the context of pediatric sarcomas. We describe the immune status using flow cytometry of peripheral blood in patients with osteosarcoma and Ewing sarcoma and demonstrat...

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Detalles Bibliográficos
Autores principales: Hingorani, Pooja, Maas, Mary L., Gustafson, Michael P., Dickman, Paul, Adams, Roberta H., Watanabe, Masayo, Eshun, Francis, Williams, James, Seidel, Matthew J., Dietz, Allan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539889/
https://www.ncbi.nlm.nih.gov/pubmed/26286851
http://dx.doi.org/10.1186/s40425-015-0082-0