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FrzA gene protects cardiomyocytes from H(2)O(2)-induced oxidative stress through restraining the Wnt/Frizzled pathway
BACKGROUND: Lately, there is accumulating evidence that the Wnt/Frizzled pathway is reactivated after myocardial infarction, the inhibition of the pathway is beneficial since it reduce of myocardial apoptosis and prevents heart failure. FrzA/Sfrp-1, a secreted frizzled-related protein and antagonist...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539933/ https://www.ncbi.nlm.nih.gov/pubmed/26282432 http://dx.doi.org/10.1186/s12944-015-0088-0 |