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Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers

Assembly of the Gag polyprotein into new viral particles in infected cells is a crucial step in the retroviral replication cycle. Currently, little is known about the onset of assembly in the cytosol. In this paper, we analyzed the cytosolic HIV-1 Gag fraction in real time in live cells using advanc...

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Detalles Bibliográficos
Autores principales: Hendrix, Jelle, Baumgärtel, Viola, Schrimpf, Waldemar, Ivanchenko, Sergey, Digman, Michelle A., Gratton, Enrico, Kräusslich, Hans-Georg, Müller, Barbara, Lamb, Don C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539982/
https://www.ncbi.nlm.nih.gov/pubmed/26283800
http://dx.doi.org/10.1083/jcb.201504006