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Paraspeckles: Paragons of functional aggregation

Low-complexity proteins undergo phase separation in vitro, forming hydrogels or liquid droplets. Whether these form in vivo, and under what conditions, is still unclear. In this issue, Hennig et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201504117) show that formation of the paraspeckle,...

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Detalles Bibliográficos
Autores principales: Courchaine, Edward, Neugebauer, Karla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539984/
https://www.ncbi.nlm.nih.gov/pubmed/26283795
http://dx.doi.org/10.1083/jcb.201507052