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The Effect of Choline Acetyltransferase Genotype on Donepezil Treatment Response in Patients with Alzheimer’s Disease

OBJECTIVE: We examined the difference in responses to donepezil between carriers and non-carriers of the A allele at the +4 position of the choline acetyltransferase (ChAT) gene in Koreans. METHODS: Patients who met the criteria for probable Alzheimer’s disease (AD) (n=199) were recruited. Among the...

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Detalles Bibliográficos
Autores principales: Lee, Kang Uk, Lee, Jung Hie, Lee, Dong Young, Youn, Jong Chul, Kim, Jeong Lan, Moon, Seok Woo, Kim, Bong-Jo, Ryu, Seung-Ho, Kim, Moon Doo, Lee, Chang-Uk, Lee, Nam-Jin, Chang, Sung Man, Kim, Young Hoon, Kim, Do Hoon, Lee, Hae-Kook, Woo, Jong Inn, Kim, Ki Woong, Jhoo, Jin Hyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540042/
https://www.ncbi.nlm.nih.gov/pubmed/26243844
http://dx.doi.org/10.9758/cpn.2015.13.2.168