The cAMP-producing agonist beraprost inhibits human vascular smooth muscle cell migration via exchange protein directly activated by cAMP

AIMS: During restenosis, vascular smooth muscle cells (VSMCs) migrate from the vascular media to the developing neointima. Preventing VSMC migration is therefore a therapeutic target for restenosis. Drugs, such as prostacyclin analogues, that increase the intracellular concentration of cyclic adenos...

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Detalles Bibliográficos
Autores principales: McKean, Jenny S., Murray, Fiona, Gibson, George, Shewan, Derryck A., Tucker, Steven J., Nixon, Graeme F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540143/
https://www.ncbi.nlm.nih.gov/pubmed/26092100
http://dx.doi.org/10.1093/cvr/cvv176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540143/
https://www.ncbi.nlm.nih.gov/pubmed/26092100
http://dx.doi.org/10.1093/cvr/cvv176

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