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The cAMP-producing agonist beraprost inhibits human vascular smooth muscle cell migration via exchange protein directly activated by cAMP
AIMS: During restenosis, vascular smooth muscle cells (VSMCs) migrate from the vascular media to the developing neointima. Preventing VSMC migration is therefore a therapeutic target for restenosis. Drugs, such as prostacyclin analogues, that increase the intracellular concentration of cyclic adenos...
Autores principales: | McKean, Jenny S., Murray, Fiona, Gibson, George, Shewan, Derryck A., Tucker, Steven J., Nixon, Graeme F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540143/ https://www.ncbi.nlm.nih.gov/pubmed/26092100 http://dx.doi.org/10.1093/cvr/cvv176 |
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