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Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor

Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies. Etk has been shown previously to provide a strong survival and metastasis signal in human prostat...

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Detalles Bibliográficos
Autores principales: Guo, W, Liu, R, Bhardwaj, G, Yang, J C, Changou, C, Ma, A-H, Mazloom, A, Chintapalli, S, Xiao, K, Xiao, W, Kumaresan, P, Sanchez, E, Yeh, C-T, Evans, C P, Patterson, R, Lam, K S, Kung, H-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540187/
https://www.ncbi.nlm.nih.gov/pubmed/25188519
http://dx.doi.org/10.1038/cddis.2014.343