Radiosensitization by a novel Bcl-2 and Bcl-X(L) inhibitor S44563 in small-cell lung cancer

Radiotherapy has a critical role in the treatment of small-cell lung cancer (SCLC). The effectiveness of radiation in SCLC remains limited as resistance results from defects in apoptosis. In the current study, we investigated whether using the Bcl-2/Bcl-X(L) inhibitor S44563 can enhance radiosensiti...

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Detalles Bibliográficos
Autores principales: Loriot, Y, Mordant, P, Dugue, D, Geneste, O, Gombos, A, Opolon, P, Guegan, J, Perfettini, J-L, Pierre, A, Berthier, L K, Kroemer, G, Soria, J C, Depil, S, Deutsch, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540189/
https://www.ncbi.nlm.nih.gov/pubmed/25232677
http://dx.doi.org/10.1038/cddis.2014.365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540189/
https://www.ncbi.nlm.nih.gov/pubmed/25232677
http://dx.doi.org/10.1038/cddis.2014.365

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