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The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression

Chemoresistance hinders the curative cancer chemotherapy. To define the role of the DNA methylation-regulated microRNA (miR) genes in the chemoresistance of bladder cancer, we performed both DNA methylomic and miRomic analyses of a multi-chemosensitive (5637) versus a multi-chemoresistant (H-bc) cel...

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Detalles Bibliográficos
Autores principales: Lv, L, Deng, H, Li, Y, Zhang, C, Liu, X, Liu, Q, Zhang, D, Wang, L, Pu, Y, Zhang, H, He, Y, Wang, Y, Yu, Y, Yu, T, Zhu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540198/
https://www.ncbi.nlm.nih.gov/pubmed/25188512
http://dx.doi.org/10.1038/cddis.2014.367