The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA

The retinoblastoma gene, rb, ensures at least its tumor suppressor function by inhibiting cell proliferation. Its role in apoptosis is more complex and less described than its role in cell cycle regulation. Rbf1, the Drosophila homolog of Rb, has been found to be pro-apoptotic in proliferative tissu...

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Detalles Bibliográficos
Autores principales: Clavier, A, Baillet, A, Rincheval-Arnold, A, Coléno-Costes, A, Lasbleiz, C, Mignotte, B, Guénal, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540203/
https://www.ncbi.nlm.nih.gov/pubmed/25188515
http://dx.doi.org/10.1038/cddis.2014.372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540203/
https://www.ncbi.nlm.nih.gov/pubmed/25188515
http://dx.doi.org/10.1038/cddis.2014.372

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