Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand

Natural thymic T regulatory (tTreg) cells maintain tolerance to self-antigen. These cells are generated in the thymus, but how this generation occurs is still controversial. Furthermore, the contribution of thymus epithelial cells to this process is still unclear, especially in humans. Using an exce...

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Detalles Bibliográficos
Autores principales: Nazzal, D, Gradolatto, A, Truffault, F, Bismuth, J, Berrih-Aknin, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540205/
https://www.ncbi.nlm.nih.gov/pubmed/25210803
http://dx.doi.org/10.1038/cddis.2014.377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540205/
https://www.ncbi.nlm.nih.gov/pubmed/25210803
http://dx.doi.org/10.1038/cddis.2014.377

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