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Restoration of Vision with Ectopic Expression of Human Rod Opsin

Many retinal dystrophies result in photoreceptor loss, but the inner retinal neurons can survive, making them potentially amenable to emerging optogenetic therapies. Here, we show that ectopically expressed human rod opsin, driven by either a non-selective or ON-bipolar cell-specific promoter, can f...

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Detalles Bibliográficos
Autores principales: Cehajic-Kapetanovic, Jasmina, Eleftheriou, Cyril, Allen, Annette E., Milosavljevic, Nina, Pienaar, Abigail, Bedford, Robert, Davis, Katherine E., Bishop, Paul N., Lucas, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540256/
https://www.ncbi.nlm.nih.gov/pubmed/26234216
http://dx.doi.org/10.1016/j.cub.2015.07.029