Cargando…
Influence of 1α, 25-dihydroxyvitamin D(3) [1, 25(OH)(2)D(3)] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes
BACKGROUND: Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 (OH)(2)D(3) has been shown to be protective of cartilage in b...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540304/ https://www.ncbi.nlm.nih.gov/pubmed/26290720 http://dx.doi.org/10.1186/s40781-014-0033-1 |