Influence of 1α, 25-dihydroxyvitamin D(3) [1, 25(OH)(2)D(3)] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes

BACKGROUND: Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 (OH)(2)D(3) has been shown to be protective of cartilage in b...

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Detalles Bibliográficos
Autores principales: Hdud, Ismail M, Loughna, Paul T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540304/
https://www.ncbi.nlm.nih.gov/pubmed/26290720
http://dx.doi.org/10.1186/s40781-014-0033-1

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