Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Signaling

Recently we have demonstrated the importance of RBPjk-dependent Notch signaling in the regulation of mesenchymal stem cell (MSC) differentiation during skeletogenesis both in vivo and in vitro. Here we further performed RBPJK loss-of-function experiments to demonstrate for the first time that RBPJK...

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Detalles Bibliográficos
Autores principales: Shang, Xifu, Luo, Zhengliang, Wang, Xudong, Jaeblon, Todd, Marymont, John V., Dong, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540435/
https://www.ncbi.nlm.nih.gov/pubmed/26285013
http://dx.doi.org/10.1371/journal.pone.0135971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540435/
https://www.ncbi.nlm.nih.gov/pubmed/26285013
http://dx.doi.org/10.1371/journal.pone.0135971

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