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Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Signaling
Recently we have demonstrated the importance of RBPjk-dependent Notch signaling in the regulation of mesenchymal stem cell (MSC) differentiation during skeletogenesis both in vivo and in vitro. Here we further performed RBPJK loss-of-function experiments to demonstrate for the first time that RBPJK...
Autores principales: | Shang, Xifu, Luo, Zhengliang, Wang, Xudong, Jaeblon, Todd, Marymont, John V., Dong, Yufeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540435/ https://www.ncbi.nlm.nih.gov/pubmed/26285013 http://dx.doi.org/10.1371/journal.pone.0135971 |
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