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A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases

The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection of a neuron. Under normal conditions two axonal cytoskeletal polymers, microtubules and neurofilaments, align longitudinally in axons and are interspersed in axonal cro...

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Detalles Bibliográficos
Autores principales: Xue, Chuan, Shtylla, Blerta, Brown, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540448/
https://www.ncbi.nlm.nih.gov/pubmed/26285012
http://dx.doi.org/10.1371/journal.pcbi.1004406