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Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc(1638N) Mice

Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the effect of diet- and genetically-induced obesity on th...

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Detalles Bibliográficos
Autores principales: Pfalzer, Anna C., Nesbeth, Paula-Dene C., Parnell, Laurence D., Iyer, Lakshmanan K., Liu, Zhenhua, Kane, Anne V., Chen, C-Y. Oliver, Tai, Albert K., Bowman, Thomas A., Obin, Martin S., Mason, Joel B., Greenberg, Andrew S., Choi, Sang-Woon, Selhub, Jacob, Paul, Ligi, Crott, Jimmy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540493/
https://www.ncbi.nlm.nih.gov/pubmed/26284788
http://dx.doi.org/10.1371/journal.pone.0135758