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Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc(1638N) Mice
Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the effect of diet- and genetically-induced obesity on th...
Autores principales: | Pfalzer, Anna C., Nesbeth, Paula-Dene C., Parnell, Laurence D., Iyer, Lakshmanan K., Liu, Zhenhua, Kane, Anne V., Chen, C-Y. Oliver, Tai, Albert K., Bowman, Thomas A., Obin, Martin S., Mason, Joel B., Greenberg, Andrew S., Choi, Sang-Woon, Selhub, Jacob, Paul, Ligi, Crott, Jimmy W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540493/ https://www.ncbi.nlm.nih.gov/pubmed/26284788 http://dx.doi.org/10.1371/journal.pone.0135758 |
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