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Derivation of an Analytical Solution to a Reaction-Diffusion Model for Autocatalytic Degradation and Erosion in Polymer Microspheres

A mathematical reaction-diffusion model is defined to describe the gradual decomposition of polymer microspheres composed of poly(D,L-lactic-co-glycolic acid) (PLGA) that are used for pharmaceutical drug delivery over extended periods of time. The partial differential equation (PDE) model treats sim...

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Detalles Bibliográficos
Autores principales: Ford Versypt, Ashlee N., Arendt, Paul D., Pack, Daniel W., Braatz, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540565/
https://www.ncbi.nlm.nih.gov/pubmed/26284787
http://dx.doi.org/10.1371/journal.pone.0135506