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Derivation of an Analytical Solution to a Reaction-Diffusion Model for Autocatalytic Degradation and Erosion in Polymer Microspheres
A mathematical reaction-diffusion model is defined to describe the gradual decomposition of polymer microspheres composed of poly(D,L-lactic-co-glycolic acid) (PLGA) that are used for pharmaceutical drug delivery over extended periods of time. The partial differential equation (PDE) model treats sim...
Autores principales: | Ford Versypt, Ashlee N., Arendt, Paul D., Pack, Daniel W., Braatz, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540565/ https://www.ncbi.nlm.nih.gov/pubmed/26284787 http://dx.doi.org/10.1371/journal.pone.0135506 |
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