Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis

Doublecortin-like kinase 1 (Dclk1), a microtubule-associated kinase, marks the fifth lineage of intestinal epithelial cells called tuft cells that function as tumor stem cells in Apc mutant models of colon cancer. In order to determine the role of Dclk1 in dextran sulfate sodium (DSS) induced coloni...

Descripción completa

Detalles Bibliográficos
Autores principales: Qu, Dongfeng, Weygant, Nathaniel, May, Randal, Chandrakesan, Parthasarathy, Madhoun, Mohammad, Ali, Naushad, Sureban, Sripathi M., An, Guangyu, Schlosser, Michael J., Houchen, Courtney W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540568/
https://www.ncbi.nlm.nih.gov/pubmed/26285154
http://dx.doi.org/10.1371/journal.pone.0134212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540568/
https://www.ncbi.nlm.nih.gov/pubmed/26285154
http://dx.doi.org/10.1371/journal.pone.0134212

Ejemplares similares