l-Ascorbyl-2-phosphate attenuates NF-κB signaling in SZ95 sebocytes without affecting IL-6 and IL-8 secretion

Acne is the most common inflammatory skin disease. Interleukin-1 (IL-1) is at the beginning of the cytokine signaling cascade and may be involved in the pathogenesis of this disorder. It activates redox-sensitive transcription factors, which induce IL-6 and IL-8 expression. Interestingly, l-ascorbyl...

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Detalles Bibliográficos
Autores principales: Ikeno, Hiroshi, Apel, Mara, Zouboulis, Christos, Luger, Thomas A., Böhm, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540786/
https://www.ncbi.nlm.nih.gov/pubmed/25894228
http://dx.doi.org/10.1007/s00403-015-1565-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540786/
https://www.ncbi.nlm.nih.gov/pubmed/25894228
http://dx.doi.org/10.1007/s00403-015-1565-z

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