Identification of Lineage-Specific Cis-Regulatory Modules Associated with Variation in Transcription Factor Binding and Chromatin Activity Using Ornstein–Uhlenbeck Models

Scoring the impact of noncoding variation on the function of cis-regulatory regions, on their chromatin state, and on the qualitative and quantitative expression levels of target genes is a fundamental problem in evolutionary genomics. A particular challenge is how to model the divergence of quantit...

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Detalles Bibliográficos
Autores principales: Naval-Sánchez, Marina, Potier, Delphine, Hulselmans, Gert, Christiaens, Valerie, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540964/
https://www.ncbi.nlm.nih.gov/pubmed/25944915
http://dx.doi.org/10.1093/molbev/msv107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540964/
https://www.ncbi.nlm.nih.gov/pubmed/25944915
http://dx.doi.org/10.1093/molbev/msv107

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