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Inhibition of hedgehog signaling reduces the side population in human malignant mesothelioma cell lines
Deregulation of crucial embryonic pathways, including hedgehog signaling, has been frequently implicated in a variety of human cancers and is emerging as an important target for anticancer therapy. This study evaluated the potential anticancer effects of cyclopamine, a chemical inhibitor of hedgehog...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541142/ https://www.ncbi.nlm.nih.gov/pubmed/26206198 http://dx.doi.org/10.1038/cgt.2015.31 |