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Beautiful small: Misleading large randomized controlled trials? The example of colloids for volume resuscitation
In anesthesia and intensive care, treatment benefits that were claimed on the basis of small or modest-sized trials have repeatedly failed to be confirmed in large randomized controlled trials. A well-designed small trial in a homogeneous patient population with high event rates could yield conclusi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541191/ https://www.ncbi.nlm.nih.gov/pubmed/26330723 http://dx.doi.org/10.4103/0970-9185.161680 |