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Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes
Human ageing affects the immune system resulting in an overall decline in immunocompetence. Although all immune cells are affected during aging, the functional capacity of T cells is most influenced and is linked to decreased responsiveness to infections and impaired differentiation. We studied age-...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541364/ https://www.ncbi.nlm.nih.gov/pubmed/26286994 http://dx.doi.org/10.1038/srep13107 |