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Gene looping facilitates TFIIH kinase-mediated termination of transcription

TFIIH is a general transcription factor with kinase and helicase activities. The kinase activity resides in the Kin28 subunit of TFIIH. The role of Kin28 kinase in the early steps of transcription is well established. Here we report a novel role of Kin28 in the termination of transcription. We show...

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Detalles Bibliográficos
Autores principales: Medler, Scott, Ansari, Athar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541409/
https://www.ncbi.nlm.nih.gov/pubmed/26286112
http://dx.doi.org/10.1038/srep12586