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Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

INTRODUCTION: The steady increase in the incidence of obesity among adults has been paralleled with higher levels of obesity-associated breast cancer. While recent studies have suggested that adipose stromal/stem cells (ASCs) isolated from obese women enhance tumorigenicity, the mechanism(s) by whic...

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Detalles Bibliográficos
Autores principales: Strong, Amy L., Ohlstein, Jason F., Biagas, Brandi A., Rhodes, Lyndsay V., Pei, Dorothy T., Tucker, H. Alan, Llamas, Claire, Bowles, Annie C., Dutreil, Maria F., Zhang, Shijia, Gimble, Jeffrey M., Burow, Matthew E., Bunnell, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541745/
https://www.ncbi.nlm.nih.gov/pubmed/26286584
http://dx.doi.org/10.1186/s13058-015-0622-z