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Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements

BACKGROUND: Endoretroviruses account for circa 8 % of all transposable elements found in the genome of humans and other animals. They represent a genetic footprint of ancestral germ-cell infections of exoviruses that is transmittable to the progeny by Mendelian segregation. Traces of human endogenou...

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Detalles Bibliográficos
Autores principales: Díaz-Carballo, David, Acikelli, Ali Haydar, Klein, Jacqueline, Jastrow, Holger, Dammann, Philipp, Wyganowski, Thomas, Guemues, Cihan, Gustmann, Sebastian, Bardenheuer, Walter, Malak, Sascha, Tefett, Nora Sophia, Khosrawipour, Veria, Giger-Pabst, Urs, Tannapfel, Andrea, Strumberg, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542094/
https://www.ncbi.nlm.nih.gov/pubmed/26260344
http://dx.doi.org/10.1186/s13046-015-0199-5