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Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements
BACKGROUND: Endoretroviruses account for circa 8 % of all transposable elements found in the genome of humans and other animals. They represent a genetic footprint of ancestral germ-cell infections of exoviruses that is transmittable to the progeny by Mendelian segregation. Traces of human endogenou...
Autores principales: | Díaz-Carballo, David, Acikelli, Ali Haydar, Klein, Jacqueline, Jastrow, Holger, Dammann, Philipp, Wyganowski, Thomas, Guemues, Cihan, Gustmann, Sebastian, Bardenheuer, Walter, Malak, Sascha, Tefett, Nora Sophia, Khosrawipour, Veria, Giger-Pabst, Urs, Tannapfel, Andrea, Strumberg, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542094/ https://www.ncbi.nlm.nih.gov/pubmed/26260344 http://dx.doi.org/10.1186/s13046-015-0199-5 |
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