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Optimising plasma levels of clozapine during metabolic interactions: a review and case report with adjunct rifampicin treatment
BACKGROUND: Clozapine is the only licensed medication for treatment-resistant schizophrenia. The metabolism of clozapine is affected by multiple pharmacokinetic interactions, so the co-administration of adjunct medications can have a significant clinical effect. The anti- tuberculosis medication rif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542109/ https://www.ncbi.nlm.nih.gov/pubmed/26265348 http://dx.doi.org/10.1186/s12888-015-0536-4 |