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Heat-Labile Enterotoxin IIa, a Platform To Deliver Heterologous Proteins into Neurons

Cholera toxin (CT) and the related heat-labile enterotoxins (LT) of Escherichia coli have been implicated as adjuvants in human therapies, but reactivity upon intranasal delivery dampened efforts to develop other clinical applications. However, each CT family member variant has unique biological pro...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Przedpelski, Amanda, Tepp, William H., Pellett, Sabine, Johnson, Eric A., Barbieri, Joseph T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542185/
https://www.ncbi.nlm.nih.gov/pubmed/26265718
http://dx.doi.org/10.1128/mBio.00734-15