Cargando…

Id2 deletion attenuates Apc-deficient ileal tumor formation

The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promote...

Descripción completa

Detalles Bibliográficos
Autores principales: Biyajima, Kyoko, Kakizaki, Fumihiko, Shen, Xiaodong, Mori, Kentaro, Sugai, Manabu, Taketo, M. Mark, Yokota, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542283/
https://www.ncbi.nlm.nih.gov/pubmed/26163528
http://dx.doi.org/10.1242/bio.012252