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Id2 deletion attenuates Apc-deficient ileal tumor formation
The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promote...
Autores principales: | Biyajima, Kyoko, Kakizaki, Fumihiko, Shen, Xiaodong, Mori, Kentaro, Sugai, Manabu, Taketo, M. Mark, Yokota, Yoshifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542283/ https://www.ncbi.nlm.nih.gov/pubmed/26163528 http://dx.doi.org/10.1242/bio.012252 |
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