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Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

The deregulation of cell polarity or cytoskeletal regulators is a common occurrence in human epithelial cancers. Moreover, there is accumulating evidence in human epithelial cancer that BTB-ZF genes, such as Bcl6 and ZBTB7A, are oncogenic. From our previous studies in the vinegar fly, Drosophila mel...

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Detalles Bibliográficos
Autores principales: Turkel, Nezaket, Portela, Marta, Poon, Carole, Li, Jason, Brumby, Anthony M., Richardson, Helena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542289/
https://www.ncbi.nlm.nih.gov/pubmed/26187947
http://dx.doi.org/10.1242/bio.012815