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Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval

Endosome-to-Golgi retrieval is an essential membrane trafficking pathway required for many important physiological processes and linked to neurodegenerative disease and infection by bacterial and viral pathogens. The prototypical cargo protein for this pathway is the cation-independent mannose 6-pho...

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Detalles Bibliográficos
Autores principales: Breusegem, Sophia Y., Seaman, Matthew N.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542293/
https://www.ncbi.nlm.nih.gov/pubmed/25464851
http://dx.doi.org/10.1016/j.celrep.2014.10.053