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Heterogeneous Tumor Subpopulations Cooperate to Drive Invasion

Clonal selection and transcriptional reprogramming (e.g., epithelial-mesenchymal transition or phenotype switching) are the predominant theories thought to underlie tumor progression. However, a “division of labor” leading to cooperation among tumor-cell subpopulations could be an additional catalys...

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Detalles Bibliográficos
Autores principales: Chapman, Anna, Fernandez del Ama, Laura, Ferguson, Jennifer, Kamarashev, Jivko, Wellbrock, Claudia, Hurlstone, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542310/
https://www.ncbi.nlm.nih.gov/pubmed/25066122
http://dx.doi.org/10.1016/j.celrep.2014.06.045