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Heterogeneous Tumor Subpopulations Cooperate to Drive Invasion
Clonal selection and transcriptional reprogramming (e.g., epithelial-mesenchymal transition or phenotype switching) are the predominant theories thought to underlie tumor progression. However, a “division of labor” leading to cooperation among tumor-cell subpopulations could be an additional catalys...
Autores principales: | Chapman, Anna, Fernandez del Ama, Laura, Ferguson, Jennifer, Kamarashev, Jivko, Wellbrock, Claudia, Hurlstone, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542310/ https://www.ncbi.nlm.nih.gov/pubmed/25066122 http://dx.doi.org/10.1016/j.celrep.2014.06.045 |
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