Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

Topological domains are key architectural building blocks of chromosomes, but their functional importance and evolutionary dynamics are not well defined. We performed comparative high-throughput chromosome conformation capture (Hi-C) in four mammals and characterized the conservation and divergence...

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Detalles Bibliográficos
Autores principales: Vietri Rudan, Matteo, Barrington, Christopher, Henderson, Stephen, Ernst, Christina, Odom, Duncan T., Tanay, Amos, Hadjur, Suzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542312/
https://www.ncbi.nlm.nih.gov/pubmed/25732821
http://dx.doi.org/10.1016/j.celrep.2015.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542312/
https://www.ncbi.nlm.nih.gov/pubmed/25732821
http://dx.doi.org/10.1016/j.celrep.2015.02.004

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